Degradation of p57(Kip2) mediated by SCF(Skp2)-dependent ubiquitylation
The abundance of the cyclin-dependent kinase (CDK) inhibitor p57(Kip2), an important regulator of cell cycle progression, is thought to be controlled by the ubiquitin-proteasome pathway. The Skp1/Cul1/F-box (SCF)-type E3 ubiquitin ligase complex SCF(Skp2) has now been shown to be responsible for reg...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2003
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC193544/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12925736/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1831009100 |
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