Dynamics of Dnmt1 interaction with the replication machinery and its role in postreplicative maintenance of DNA methylation

Postreplicative maintenance of genomic methylation patterns was proposed to depend largely on the binding of DNA methyltransferase 1 (Dnmt1) to PCNA, a core component of the replication machinery. We investigated how the slow and discontinuous DNA methylation could be mechanistically linked with fas...

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Autors principals: Schermelleh, Lothar, Haemmer, Andrea, Spada, Fabio, Rösing, Nicole, Meilinger, Daniela, Rothbauer, Ulrich, Cardoso, M. Cristina, Leonhardt, Heinrich
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2007
Matèries:
Molecular Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1934996/
https://ncbi.nlm.nih.gov/pubmed/17576694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm432
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