Dynamics of Dnmt1 interaction with the replication machinery and its role in postreplicative maintenance of DNA methylation

Postreplicative maintenance of genomic methylation patterns was proposed to depend largely on the binding of DNA methyltransferase 1 (Dnmt1) to PCNA, a core component of the replication machinery. We investigated how the slow and discontinuous DNA methylation could be mechanistically linked with fas...

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Bibliographic Details
Main Authors: Schermelleh, Lothar, Haemmer, Andrea, Spada, Fabio, Rösing, Nicole, Meilinger, Daniela, Rothbauer, Ulrich, Cardoso, M. Cristina, Leonhardt, Heinrich
Format: Artigo
Language:Inglês
Published: Oxford University Press 2007
Subjects:
Molecular Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1934996/
https://ncbi.nlm.nih.gov/pubmed/17576694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm432
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