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Antisense oligonucleotide induced exon skipping and the dystrophin gene transcript: cocktails and chemistries
BACKGROUND: Antisense oligonucleotides (AOs) can interfere with exon recognition and intron removal during pre-mRNA processing, and induce excision of a targeted exon from the mature gene transcript. AOs have been used in vitro and in vivo to redirect dystrophin pre-mRNA processing in human and anim...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2007
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1933433/ https://ncbi.nlm.nih.gov/pubmed/17601349 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-8-57 |
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