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Multiple exon skipping strategies to by-pass dystrophin mutations

Manipulation of dystrophin pre-mRNA processing offers the potential to overcome mutations in the dystrophin gene that would otherwise lead to Duchenne muscular dystrophy. Dystrophin mutations will require the removal of one or more exons to restore the reading frame and in some cases, multiple exon...

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Détails bibliographiques
Auteurs principaux: Adkin, Carl F., Meloni, Penelope L., Fletcher, Susan, Adams, Abbie M., Muntoni, Francesco, Wong, Brenda, Wilton, Steve D.
Format: Artigo
Langue:Inglês
Publié: Pergamon Press 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488593/
https://ncbi.nlm.nih.gov/pubmed/22182525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nmd.2011.10.007
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