Structures of phi29 DNA polymerase complexed with substrate: the mechanism of translocation in B-family polymerases

Replicative DNA polymerases (DNAPs) move along template DNA in a processive manner. The structural basis of the mechanism of translocation has been better studied in the A-family of polymerases than in the B-family of replicative polymerases. To address this issue, we have determined the X-ray cryst...

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Detalhes bibliográficos
Main Authors: Berman, Andrea J, Kamtekar, Satwik, Goodman, Jessica L, Lázaro, José M, de Vega, Miguel, Blanco, Luis, Salas, Margarita, Steitz, Thomas A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1933411/
https://ncbi.nlm.nih.gov/pubmed/17611604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601780
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