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The φ29 DNA polymerase:protein-primer structure suggests a model for the initiation to elongation transition
The absolute requirement for primers in the initiation of DNA synthesis poses a problem for replicating the ends of linear chromosomes. The DNA polymerase of bacteriophage φ29 solves this problem by using a serine hydroxyl of terminal protein to prime replication. The 3.0 Å resolution structure show...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2006
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1422159/ https://ncbi.nlm.nih.gov/pubmed/16511564 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601027 |
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