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Inhibition of c-Myc activity by ribosomal protein L11

The c-Myc oncoprotein promotes cell growth by enhancing ribosomal biogenesis through upregulation of RNA polymerases I-, II-, and III-dependent transcription. Overexpression of c-Myc and aberrant ribosomal biogenesis leads to deregulated cell growth and tumorigenesis. Hence, c-Myc activity and ribos...

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Bibliografski detalji
Glavni autori: Dai, Mu-Shui, Arnold, Hugh, Sun, Xiao-Xin, Sears, Rosalie, Lu, Hua
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1933407/
https://ncbi.nlm.nih.gov/pubmed/17599065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601776
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