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Pharmacokinetics of the Antiviral Agent β-d-2′-Deoxy-2′-Fluoro-2′-C-Methylcytidine in Rhesus Monkeys

β-d-2′-Deoxy-2′-fluoro-2′-C-methylcytidine (PSI-6130) is an effective inhibitor of hepatitis C virus (HCV) replication in vitro. The purpose of this study was to evaluate the single-dose pharmacokinetics of PSΙ-6130 in rhesus monkeys following intravenous (i.v.) and oral administration. Noncompartme...

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Detaylı Bibliyografya
Asıl Yazarlar: Asif, Ghazia, Hurwitz, Selwyn J., Shi, Junxing, Hernandez-Santiago, Brenda I., Schinazi, Raymond F.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2007
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1932527/
https://ncbi.nlm.nih.gov/pubmed/17562805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00193-07
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