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Pharmacokinetics of the Anti-Human Immunodeficiency Virus Agent 1-(β-d-Dioxolane)Thymine in Rhesus Monkeys

β-d-Dioxolane-thymine (D-DOT) has potent and selective in vitro activity against several clinically important resistant human immunodeficiency virus (HIV) mutants and is in advanced preclinical development. Therefore, the single-dose intravenous and oral pharmacokinetics of D-DOT were studied with t...

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Autori principali: Asif, Ghazia, Hurwitz, Selwyn J., Obikhod, Aleksandr, Delinsky, David, Narayanasamy, Janarthanan, Chu, Chung K., McClure, Harold M., Schinazi, Raymond F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1913250/
https://ncbi.nlm.nih.gov/pubmed/17485498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01498-06
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