Pharmacology and Pharmacokinetics of the Antiviral Agent β-d-2′,3′-Dideoxy-3′-Oxa-5-Fluorocytidine in Cells and Rhesus Monkeys

β-d-2′,3′-Dideoxy-3′-oxa-5-fluorocytidine (d-FDOC) is an effective inhibitor of human immunodeficiency virus 1 (HIV-1) and HIV-2, simian immunodeficiency virus, and hepatitis B virus (HBV) in vitro. The purpose of this study was to evaluate the intracellular metabolism of d-FDOC in human hepatoma (H...

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Autores principales: Hernandez-Santiago, Brenda I., Chen, Huachun, Asif, Ghazia, Beltran, Thierry, Mao, Shuli, Hurwitz, Selwyn J., Grier, Jason, McClure, Harold M., Chu, Chung K., Liotta, Dennis C., Schinazi, Raymond F.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2005
Materias:
Antiviral Agents
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1168701/
https://ncbi.nlm.nih.gov/pubmed/15980324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.7.2589-2597.2005
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