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Abnormal phosphorylation of tau and the mechanism of Alzheimer neurofibrillary degeneration: Sequestration of microtubule-associated proteins 1 and 2 and the disassembly of microtubules by the abnormal tau

The microtubule-associated protein (MAP) tau is abnormally hyperphosphorylated in Alzheimer disease and accumulates in neurons undergoing neurofibrillary degeneration. In the present study, the associations of the Alzheimer-hyperphosphorylated tau (AD P-tau) with the high molecular weight MAPs (HMW-...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Alonso, Alejandra del C., Grundke-Iqbal, Inge, Barra, Héctor S., Iqbal, Khalid
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The National Academy of Sciences of the USA 1997
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC19321/
https://ncbi.nlm.nih.gov/pubmed/8990203
Etiketak: Etiketa erantsi
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