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Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology.

A monoclonal antibody to the microtubule-associated protein tau (tau) labeled some neurofibrillary tangles and plaque neurites, the two major locations of paired-helical filaments (PHF), in Alzheimer disease brain. The antibody also labeled isolated PHF that had been repeatedly washed with NaDodSO4....

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Detalhes bibliográficos
Main Authors: Grundke-Iqbal, I, Iqbal, K, Tung, Y C, Quinlan, M, Wisniewski, H M, Binder, L I
Formato: Artigo
Idioma:Inglês
Publicado em: 1986
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC323854/
https://ncbi.nlm.nih.gov/pubmed/3088567
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