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A natural transactivation mutation in the thyroid hormone β receptor: Impaired interaction with putative transcriptional mediators
The syndrome of resistance to thyroid hormone is characterized by elevated serum free thyroid hormones, failure to suppress pituitary thyrotropin secretion, and variable peripheral refractoriness to hormone action. Here we describe a novel leucine to valine mutation in codon 454 (L454V) of the thyro...
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| Main Authors: | , , , , , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
The National Academy of Sciences of the USA
1997
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC19304/ https://ncbi.nlm.nih.gov/pubmed/8990194 |
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