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Tuning Ion Coordination Architectures to Enable Selective Partitioning

K(+) ions seemingly permeate K-channels rapidly because channel binding sites mimic coordination of K(+) ions in water. Highly selective ion discrimination should occur when binding sites form rigid cavities that match K(+), but not the smaller Na(+), ion size or when binding sites are composed of s...

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Autori principali: Varma, Sameer, Rempe, Susan B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1929028/
https://ncbi.nlm.nih.gov/pubmed/17513348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.107482
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