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Tuning Ion Coordination Architectures to Enable Selective Partitioning
K(+) ions seemingly permeate K-channels rapidly because channel binding sites mimic coordination of K(+) ions in water. Highly selective ion discrimination should occur when binding sites form rigid cavities that match K(+), but not the smaller Na(+), ion size or when binding sites are composed of s...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Biophysical Society
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1929028/ https://ncbi.nlm.nih.gov/pubmed/17513348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.107482 |
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