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K(+)/Na(+) selectivity in K-channels and Valinomycin: Over-coordination Vs Cavity-size constraints
K-channels and valinomycin molecules share the exquisite ability to select K(+) over Na(+) ions. Highly selective K-channels maintain a special local environment around their binding sites devoid of competing hydrogen bond donor groups, which enables spontaneous transfer of K(+) from states of low c...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2390915/ https://ncbi.nlm.nih.gov/pubmed/18155244 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.11.059 |
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