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K(+)/Na(+) selectivity in K-channels and Valinomycin: Over-coordination Vs Cavity-size constraints

K-channels and valinomycin molecules share the exquisite ability to select K(+) over Na(+) ions. Highly selective K-channels maintain a special local environment around their binding sites devoid of competing hydrogen bond donor groups, which enables spontaneous transfer of K(+) from states of low c...

詳細記述

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書誌詳細
主要な著者: Varma, Sameer, Sabo, Dubravko, Rempe, Susan B.
フォーマット: Artigo
言語:Inglês
出版事項: 2007
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2390915/
https://ncbi.nlm.nih.gov/pubmed/18155244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.11.059
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