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The Predominant Role of Coordination Number in Potassium Channel Selectivity

Potassium channels are exquisitely selective, allowing K(+) to pass across cell membranes while blocking other ion types. Here we demonstrate that the number of carbonyl oxygen atoms that surround permeating ions is the most important factor in determining ion selectivity rather than the size of the...

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Détails bibliographiques
Auteurs principaux: Thomas, Michael, Jayatilaka, Dylan, Corry, Ben
Format: Artigo
Langue:Inglês
Publié: Biophysical Society 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1989715/
https://ncbi.nlm.nih.gov/pubmed/17573427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.108167
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