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In vitro selection of a purine nucleotide-specific hammerheadlike ribozyme

The in vitro selection for an intramolecular AUG-cleaving hammerhead-like ribozyme is described. One of the ribozymes selected was found to cleave after this triplet, both intramolecularly and intermolecularly, with rates comparable to the rate of the native GUC-cleaving hammerhead ribozyme. Althoug...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Vaish, Narendra K., Heaton, Paul A., Fedorova, Olga, Eckstein, Fritz
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The National Academy of Sciences 1998
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC19281/
https://ncbi.nlm.nih.gov/pubmed/9482855
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