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In vitro selection of a 5′-purine ribonucleotide transferase ribozyme

Here we report in vitro selection of a novel ribozyme that catalyzes the 5′-nucleotidyl transfer reaction forming the 2′–5′ phosphodiester bond. This ribozyme was retrieved as a sole sequence in the pool enriched for the 5′-triphosphate-dependent activities in incorporating ATP-γS. The originally se...

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Detalles Bibliográficos
Main Authors: Kang, Taek Jin, Suga, Hiroaki
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2007
Assuntos:
RNA
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1919479/
https://ncbi.nlm.nih.gov/pubmed/17567602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm438
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