Validation of the SCID-hu Thy/Liv Mouse Model with Four Classes of Licensed Antiretrovirals

BACKGROUND: The SCID-hu Thy/Liv mouse model of HIV-1 infection is a useful platform for the preclinical evaluation of antiviral efficacy in vivo. We performed this study to validate the model with representatives of all four classes of licensed antiretrovirals. METHODOLOGY/PRINCIPAL FINDINGS: Endpoi...

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Detalhes bibliográficos
Main Authors: Stoddart, Cheryl A., Bales, Cheryl A., Bare, Jennifer C., Chkhenkeli, George, Galkina, Sofiya A., Kinkade, April N., Moreno, Mary E., Rivera, José M., Ronquillo, Rollie E., Sloan, Barbara, Black, Paul L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1925140/
https://ncbi.nlm.nih.gov/pubmed/17668043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000655
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