Validation of the SCID-hu Thy/Liv Mouse Model with Four Classes of Licensed Antiretrovirals

BACKGROUND: The SCID-hu Thy/Liv mouse model of HIV-1 infection is a useful platform for the preclinical evaluation of antiviral efficacy in vivo. We performed this study to validate the model with representatives of all four classes of licensed antiretrovirals. METHODOLOGY/PRINCIPAL FINDINGS: Endpoi...

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Main Authors: Stoddart, Cheryl A., Bales, Cheryl A., Bare, Jennifer C., Chkhenkeli, George, Galkina, Sofiya A., Kinkade, April N., Moreno, Mary E., Rivera, José M., Ronquillo, Rollie E., Sloan, Barbara, Black, Paul L.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2007
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1925140/
https://ncbi.nlm.nih.gov/pubmed/17668043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000655
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