Human Herpesvirus 6 (HHV-6) Causes Severe Thymocyte Depletion in SCID-hu Thy/Liv Mice

Human herpesvirus 6 (HHV-6) is a potentially immunosuppressive agent that may act as a cofactor in the progression of AIDS. Here, we describe the first small animal model of HHV-6 infection. HHV-6 subgroup A, strain GS, efficiently infected the human thymic tissue implanted in SCID-hu Thy/Liv mice,...

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Autori principali: Gobbi, Alberto, Stoddart, Cheryl A., Malnati, Mauro S., Locatelli, Giuseppe, Santoro, Fabio, Abbey, Nancy W., Bare, Christopher, Linquist-Stepps, Valerie, Moreno, Mary Beth, Herndier, Brian G., Lusso, Paolo, McCune, Joseph M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2192958/
https://ncbi.nlm.nih.gov/pubmed/10377191
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