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Persistence of recombinant adenovirus in vivo is not dependent on vector DNA replication.

Recombinant adenovirus vectors represent an efficient means of transferring genes into many different organs. The first-generation E1-deleted vector genome remains episomal and, in the absence of host immunity, persists long-term in quiescent tissues such as the liver. The mechanism(s) which allows...

Cur síos iomlán

Sábháilte in:
Sonraí bibleagrafaíochta
Foilsithe in:J Virol
Príomhchruthaitheoirí: Nelson, J E, Kay, M A
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: American Society for Microbiology (ASM) 1997
Ábhair:
Rochtain ar líne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC192362/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9343256/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.11.8902-8907.1997
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