Persistence of recombinant adenovirus in vivo is not dependent on vector DNA replication.
Recombinant adenovirus vectors represent an efficient means of transferring genes into many different organs. The first-generation E1-deleted vector genome remains episomal and, in the absence of host immunity, persists long-term in quiescent tissues such as the liver. The mechanism(s) which allows...
Spremljeno u:
| Izdano u: | J Virol |
|---|---|
| Glavni autori: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology (ASM)
1997
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC192362/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9343256/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.11.8902-8907.1997 |
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