Transformation and tumorigenic properties of a mutant polyomavirus containing a middle T antigen defective in Shc binding.
Polyomavirus middle T antigen is phosphorylated on several tyrosine residues which act as binding sites for cellular proteins, including phosphatidylinositol 3-kinase, Shc, and phospholipase C-gamma. In this report we describe the transforming properties and tumor-inducing ability of a polyomavirus...
Uloženo v:
| Vydáno v: | J Virol |
|---|---|
| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Microbiology (ASM)
1997
|
| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191900/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9261344/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.9.6279-6286.1997 |
| Tagy: |
Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!
|