Transformation and tumorigenic properties of a mutant polyomavirus containing a middle T antigen defective in Shc binding.
Polyomavirus middle T antigen is phosphorylated on several tyrosine residues which act as binding sites for cellular proteins, including phosphatidylinositol 3-kinase, Shc, and phospholipase C-gamma. In this report we describe the transforming properties and tumor-inducing ability of a polyomavirus...
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| Publicado no: | J Virol |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191900/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9261344/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.9.6279-6286.1997 |
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