Transformation and tumorigenic properties of a mutant polyomavirus containing a middle T antigen defective in Shc binding.

Polyomavirus middle T antigen is phosphorylated on several tyrosine residues which act as binding sites for cellular proteins, including phosphatidylinositol 3-kinase, Shc, and phospholipase C-gamma. In this report we describe the transforming properties and tumor-inducing ability of a polyomavirus...

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Pubblicato in:	J Virol
Autori principali:	Yi, X, Peterson, J, Freund, R
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1997
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191900/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9261344/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.9.6279-6286.1997
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