Mismatch Repair Genes on Chromosomes 2p and 3p Account for a Major Share of Hereditary Nonpolyposis Colorectal Cancer Families Evaluable by Linkage

Two susceptibility loci for hereditary nonpolyposis colo-rectal cancer (HNPCC) have been identified, and each contains a mismatch repair gene: MSH2 on chromosome 2p and MLH1 on chromosome 3p. We studied the involvement of these loci in 13 large HNPCC kindreds originating from three different contine...

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Main Authors: Nyström-Lahti, Minna, Parsons, Ramon, Sistonen, Pertti, Pylkkänen, Lea, Aaltonen, Lauri A., Leach, Fredrick S., Hamilton, Stanley R., Watson, Patrice, Bronson, Earlene, Fusaro, Ramon, Cavalieri, Jennifer, Lynch, Jane, Lanspa, Stephen, Smyrk, Tom, Lynch, Patrick, Drouhard, Thomas, Kinzler, Kenneth W., Vogelstein, Bert, Lynch, Henry T., de la Chapelle, Albert, Peltomäki, Päivi
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1994
Ábhair:
Original Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1918295/
https://ncbi.nlm.nih.gov/pubmed/7942843
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