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Close linkage to chromosome 3p and conservation of ancestral founding haplotype in hereditary nonpolyposis colorectal cancer families.

A susceptibility to hereditary nonpolyposis colorectal cancer (HNPCC) was recently shown to be due to mutations in the MSH2 gene on chromosome 2p. A second susceptibility locus has been mapped to chromosome 3p in two families. The present report describes the results of a genetic study of Finnish HN...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Nyström-Lahti, M, Sistonen, P, Mecklin, J P, Pylkkänen, L, Aaltonen, L A, Järvinen, H, Weissenbach, J, de la Chapelle, A, Peltomäki, P
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1994
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44136/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8016114/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.13.6054
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