Plasma membrane targeting of chimeric intracisternal A-type particle polyproteins leads to particle release and specific activation of the viral proteinase.

Retrovirus morphogenesis involves assembly of structural Gag polyproteins with subsequent budding from the plasma membrane, followed by proteolytic cleavage by the viral proteinase (PR) and extracellular maturation to the infectious virion. Intracisternal A-type particles (IAPs) are defective retrov...

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Bibliografische gegevens

Gepubliceerd in:	J Virol
Hoofdauteurs:	Welker, R, Janetzko, A, Krausslich, H G
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	American Society for Microbiology (ASM) 1997
Onderwerpen:	Research Article
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191756/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9188588/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.7.5209-5217.1997
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