Plasma membrane targeting of chimeric intracisternal A-type particle polyproteins leads to particle release and specific activation of the viral proteinase.

Eitemau Tebyg

• Human immunodeficiency virus proteinase dimer as component of the viral polyprotein prevents particle assembly and viral infectivity.
  gan: Kräusslich, H G
  Cyhoeddwyd: (1991)
• Transport of the Intracisternal A-Type Particle Gag Polyprotein to the Endoplasmic Reticulum Is Mediated by the Signal Recognition Particle
  gan: Fehrmann, Frauke, et al.
  Cyhoeddwyd: (2003)
• Chimeric picornavirus polyproteins demonstrate a common 3C proteinase substrate specificity.
  gan: Dewalt, P G, et al.
  Cyhoeddwyd: (1989)
• A large deletion in the matrix domain of the human immunodeficiency virus gag gene redirects virus particle assembly from the plasma membrane to the endoplasmic reticulum.
  gan: Fäcke, M, et al.
  Cyhoeddwyd: (1993)
• Specific inhibitor of human immunodeficiency virus proteinase prevents the cytotoxic effects of a single-chain proteinase dimer and restores particle formation.
  gan: Kräusslich, H G
  Cyhoeddwyd: (1992)