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Cleavage of Human Immunodeficiency Virus Type 1 Proteinase from the N-Terminally Adjacent p6* Protein Is Essential for Efficient Gag Polyprotein Processing and Viral Infectivity

Maturation of infectious human immunodeficiency virus (HIV) particles requires proteolytic cleavage of the structural polyproteins by the viral proteinase (PR), which is itself encoded as part of the Gag-Pol polyprotein. Expression of truncated PR-containing sequences in heterologous systems has mos...

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Main Authors: Tessmer, Uwe, Kräusslich, Hans-Georg
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 1998
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC109854/
https://ncbi.nlm.nih.gov/pubmed/9525682
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