Uracil DNA glycosylase specifically interacts with Vpr of both human immunodeficiency virus type 1 and simian immunodeficiency virus of sooty mangabeys, but binding does not correlate with cell cycle arrest.

The Vpr protein encoded by human immunodeficiency virus type 1 (HIV-1) is important for growth of virus in macrophages and prevents infected cells from passing into mitosis (G2 arrest). The cellular target for these functions is not known, but Vpr of HIV-1 and the related Vpr from simian immunodefic...

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Bibliografiske detaljer

Udgivet i:	J Virol
Principais autores:	Selig, L, Benichou, S, Rogel, M E, Wu, L I, Vodicka, M A, Sire, J, Benarous, R, Emerman, M
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1997
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191711/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9151883/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.6.4842-4846.1997
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