Uracil DNA glycosylase specifically interacts with Vpr of both human immunodeficiency virus type 1 and simian immunodeficiency virus of sooty mangabeys, but binding does not correlate with cell cycle arrest.
The Vpr protein encoded by human immunodeficiency virus type 1 (HIV-1) is important for growth of virus in macrophages and prevents infected cells from passing into mitosis (G2 arrest). The cellular target for these functions is not known, but Vpr of HIV-1 and the related Vpr from simian immunodefic...
Shranjeno v:
| izdano v: | J Virol |
|---|---|
| Principais autores: | , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology (ASM)
1997
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191711/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9151883/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.6.4842-4846.1997 |
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