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Regulation of human basophil function by phosphatase inhibitors.

1. Okadaic acid, a cell permeant inhibitor of protein serine/threonine phosphatases (PPs), attenuated the IgE-mediated release of the pre-formed mediator, histamine from human basophils in a time- and dose-dependent manner. Optimal inhibition (77 +/- 4%, P < 0.0001) of histamine release was obser...

詳細記述

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書誌詳細
主要な著者: Peirce, M. J., Warner, J. A., Munday, M. R., Peachell, P. T.
フォーマット: Artigo
言語:Inglês
出版事項: 1996
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1915864/
https://ncbi.nlm.nih.gov/pubmed/8886433
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