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Regulation of human basophil function by phosphatase inhibitors.

1. Okadaic acid, a cell permeant inhibitor of protein serine/threonine phosphatases (PPs), attenuated the IgE-mediated release of the pre-formed mediator, histamine from human basophils in a time- and dose-dependent manner. Optimal inhibition (77 +/- 4%, P < 0.0001) of histamine release was obser...

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Bibliografische gegevens
Hoofdauteurs: Peirce, M. J., Warner, J. A., Munday, M. R., Peachell, P. T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1996
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1915864/
https://ncbi.nlm.nih.gov/pubmed/8886433
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