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Preliminary characterization of the role of protein serine/ threonine phosphatases in the regulation of human lung mast cell function
1. Okadaic acid, a cell permeant inhibitor of protein serine/threonine phosphatases (PPs), attenuated the IgE-dependent release of mediators from human lung mast cells (HLMC). The concentration of okadaic acid required to inhibit by 50% (IC(50)) the IgE-dependent release of histamine was 0.2 μM. Oka...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
1997
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1564379/ https://ncbi.nlm.nih.gov/pubmed/9117116 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0700915 |
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