Preliminary characterization of the role of protein serine/ threonine phosphatases in the regulation of human lung mast cell function

1. Okadaic acid, a cell permeant inhibitor of protein serine/threonine phosphatases (PPs), attenuated the IgE-dependent release of mediators from human lung mast cells (HLMC). The concentration of okadaic acid required to inhibit by 50% (IC(50)) the IgE-dependent release of histamine was 0.2 μM. Oka...

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Bibliographic Details
Main Authors: Peirce, Matthew J, Cox, Sarah E, Munday, Michael R, Peachell, Peter T
Format: Artigo
Language:Inglês
Published: 1997
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Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564379/
https://ncbi.nlm.nih.gov/pubmed/9117116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0700915
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