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Effects of phosphodiesterase inhibitors on human lung mast cell and basophil function
1. The non-hydrolysable cyclic AMP analogue, dibutyryl (Bu(2))-cyclic AMP, inhibited the stimulated release of histamine from both basophils and human lung mast cells (HLMC) in a dose-dependent manner. The concentrations required to inhibit histamine release by 50% (IC(50)) were 0.8 and 0.7 mM in ba...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
1997
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1564674/ https://ncbi.nlm.nih.gov/pubmed/9154339 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701115 |
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