Perturbation of the p53 response by human papillomavirus type 16 E7.

The p53 tumor suppressor protein can induce both cell cycle arrest and apoptosis in DNA-damaged cells. In human carcinoma cell lines expressing wild-type p53, expression of E7 allowed the continuation of full cell cycle progression following DNA damage, indicating that E7 can overcome both G1 and G2...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Hickman, E S, Bates, S, Vousden, K H
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191520/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9094645/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.5.3710-3718.1997
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