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Perturbation of the p53 response by human papillomavirus type 16 E7.

The p53 tumor suppressor protein can induce both cell cycle arrest and apoptosis in DNA-damaged cells. In human carcinoma cell lines expressing wild-type p53, expression of E7 allowed the continuation of full cell cycle progression following DNA damage, indicating that E7 can overcome both G1 and G2...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Hickman, E S, Bates, S, Vousden, K H
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1997
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC191520/
https://ncbi.nlm.nih.gov/pubmed/9094645
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