Perturbation of the p53 response by human papillomavirus type 16 E7.
The p53 tumor suppressor protein can induce both cell cycle arrest and apoptosis in DNA-damaged cells. In human carcinoma cell lines expressing wild-type p53, expression of E7 allowed the continuation of full cell cycle progression following DNA damage, indicating that E7 can overcome both G1 and G2...
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| Pubblicato in: | J Virol |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology (ASM)
1997
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191520/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9094645/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.5.3710-3718.1997 |
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