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Regions of human papillomavirus type 16 E7 oncoprotein required for immortalization of human keratinocytes.

Binding of the retinoblastoma gene product (pRB) by viral oncoproteins, including the E7 of human papillomavirus type 16 (HPV 16), is thought to be important in transformation of cells. One of the steps in transformation is the immortalization process. Here we show that mutations in E7 within the fu...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Jewers, R J, Hildebrandt, P, Ludlow, J W, Kell, B, McCance, D J
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC240854/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1310752/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.3.1329-1335.1992
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