Regions of human papillomavirus type 16 E7 oncoprotein required for immortalization of human keratinocytes.

Binding of the retinoblastoma gene product (pRB) by viral oncoproteins, including the E7 of human papillomavirus type 16 (HPV 16), is thought to be important in transformation of cells. One of the steps in transformation is the immortalization process. Here we show that mutations in E7 within the fu...

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Main Authors: Jewers, R J, Hildebrandt, P, Ludlow, J W, Kell, B, McCance, D J
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1992
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC240854/
https://ncbi.nlm.nih.gov/pubmed/1310752
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