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Regions of human papillomavirus type 16 E7 oncoprotein required for immortalization of human keratinocytes.

Binding of the retinoblastoma gene product (pRB) by viral oncoproteins, including the E7 of human papillomavirus type 16 (HPV 16), is thought to be important in transformation of cells. One of the steps in transformation is the immortalization process. Here we show that mutations in E7 within the fu...

詳細記述

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書誌詳細
主要な著者: Jewers, R J, Hildebrandt, P, Ludlow, J W, Kell, B, McCance, D J
フォーマット: Artigo
言語:Inglês
出版事項: 1992
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC240854/
https://ncbi.nlm.nih.gov/pubmed/1310752
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