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Regions of human papillomavirus type 16 E7 oncoprotein required for immortalization of human keratinocytes.

Binding of the retinoblastoma gene product (pRB) by viral oncoproteins, including the E7 of human papillomavirus type 16 (HPV 16), is thought to be important in transformation of cells. One of the steps in transformation is the immortalization process. Here we show that mutations in E7 within the fu...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Jewers, R J, Hildebrandt, P, Ludlow, J W, Kell, B, McCance, D J
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1992
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC240854/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1310752/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.3.1329-1335.1992
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