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Structure-based mutagenesis of the catalytic domain of human immunodeficiency virus type 1 integrase.

Two different crystal structures of the human immunodeficiency virus type 1 (HIV-1) integrase (IN) catalytic domain were analyzed for interactions at the enzyme active site. Gln-62 and Glu-92 interact with active-site residue Asp-64, and Lys-136 interacts with active-site residue Asp-116 across a di...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Engelman, A, Liu, Y, Chen, H, Farzan, M, Dyda, F
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1997
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC191497/
https://ncbi.nlm.nih.gov/pubmed/9094622
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