Role of CCR5 in infection of primary macrophages and lymphocytes by macrophage-tropic strains of human immunodeficiency virus: resistance to patient-derived and prototype isolates resulting from the delta ccr5 mutation.

The alpha-chemokine receptor fusin (CXCR-4) and beta-chemokine receptor CCR5 serve as entry cofactors for T-cell (T)-tropic and macrophage (M)-tropic human immunodeficiency virus type 1 (HIV-1) strains, respectively, when expressed with CD4 in otherwise nonpermissive cells. Some M-tropic and dual-tr...

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Vydáno v:	J Virol
Hlavní autoři:	Rana, S, Besson, G, Cook, D G, Rucker, J, Smyth, R J, Yi, Y, Turner, J D, Guo, H H, Du, J G, Peiper, S C, Lavi, E, Samson, M, Libert, F, Liesnard, C, Vassart, G, Doms, R W, Parmentier, M, Collman, R G
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1997
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191454/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9060685/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.4.3219-3227.1997
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Role of CCR5 in infection of primary macrophages and lymphocytes by macrophage-tropic strains of human immunodeficiency virus: resistance to patient-derived and prototype isolates resulting from the delta ccr5 mutation.

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