Utilization of chemokine receptors, orphan receptors, and herpesvirus-encoded receptors by diverse human and simian immunodeficiency viruses.

Human immunodeficiency virus type 1 (HIV-1) requires both CD4 and a coreceptor to infect cells. Macrophage-tropic (M-tropic) HIV-1 strains utilize the chemokine receptor CCR5 in conjunction with CD4 to infect cells, while T-cell-tropic (T-tropic) strains generally utilize CXCR4 as a coreceptor. Some...

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Detalhes bibliográficos
Main Authors: Rucker, J, Edinger, A L, Sharron, M, Samson, M, Lee, B, Berson, J F, Yi, Y, Margulies, B, Collman, R G, Doranz, B J, Parmentier, M, Doms, R W
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC230200/
https://ncbi.nlm.nih.gov/pubmed/9371556
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