Role of CCR5 in infection of primary macrophages and lymphocytes by macrophage-tropic strains of human immunodeficiency virus: resistance to patient-derived and prototype isolates resulting from the delta ccr5 mutation.

The alpha-chemokine receptor fusin (CXCR-4) and beta-chemokine receptor CCR5 serve as entry cofactors for T-cell (T)-tropic and macrophage (M)-tropic human immunodeficiency virus type 1 (HIV-1) strains, respectively, when expressed with CD4 in otherwise nonpermissive cells. Some M-tropic and dual-tr...

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Detalhes bibliográficos
Main Authors: Rana, S, Besson, G, Cook, D G, Rucker, J, Smyth, R J, Yi, Y, Turner, J D, Guo, H H, Du, J G, Peiper, S C, Lavi, E, Samson, M, Libert, F, Liesnard, C, Vassart, G, Doms, R W, Parmentier, M, Collman, R G
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC191454/
https://ncbi.nlm.nih.gov/pubmed/9060685
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