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CD4-independent, CCR5-dependent infection of brain capillary endothelial cells by a neurovirulent simian immunodeficiency virus strain

Brain capillary endothelial cells (BCECs) are targets of CD4-independent infection by HIV-1 and simian immunodeficiency virus (SIV) strains in vitro and in vivo. Infection of BCECs may provide a portal of entry for the virus into the central nervous system and could disrupt blood–brain barrier funct...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Edinger, Aimee L., Mankowski, Joseph L., Doranz, Benjamin J., Margulies, Barry J., Lee, Benhur, Rucker, Joseph, Sharron, Matthew, Hoffman, Trevor L., Berson, Joanne F., Zink, M. Christine, Hirsch, Vanessa M., Clements, Janice E., Doms, Robert W.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1997
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC25107/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9405683/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.26.14742
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